College Football Week 13: Preview, Predictions, Perspective

With a number of top playoff hopefuls on a bye or playing FCS or other favorable foes, it’s a lighter week on the college football slate than the rest of November.

But that doesn’t mean Week 13 is lacking marquee games.

Two clashes for ranked teams with major College Football Playoff implications headline the schedule Saturday.

We broke down the five best games more in depth here, but let’s cover the entire top-25 schedule and make some predictions.

John Mateer #10 of the Oklahoma Sooners rushes against the Alabama Crimson Tide during the third quarter at Bryant-Denny Stadium on November 15, 2025 in Tuscaloosa, Alabama.
Photo by Kevin C. Cox/Getty Images

RELATED: Week 13’s 5 Best Games

College Football Top 25 Schedule, Score Predictions

(All game times ET; all point spreads via ESPN Bet.)

Rutgers (5-5, 2-5 Big Ten) at No. 1 Ohio State (10-0, 7-0), 12 p.m. on Fox: Since its 14-7 season-opening win over Texas, Ohio State has won every other game by 18 or more points (usually much more). The big final hurdle for the top-ranked Buckeyes comes next week on the road vs. rival Michigan. Ohio State just needs to take care of business Saturday as a 31.5-point favorite and maybe give QB Julian Sayin a boost in the Heisman Trophy race as he enters the weekend behind Indiana QB Fernando Mendoza, per the latest odds. Prediction: Ohio State 51, Rutgers 14

Samford (1-10) at No. 3 Texas A&M (10-0), 12 p.m. on SEC Network+: The unbeaten Aggies get a light week before closing the regular season at Texas. Samford is an FCS-level team — and not a good one. The Aggies are 54.5-point favorites. Prediction: Texas A&M 66, Samford 3

No. 23 Missouri (7-3, 3-3 SEC) at No. 8 Oklahoma (8-2, 4-2), 12 p.m. on ABC: The Sooners have to avoid a letdown after the high of upsetting Alabama in Tuscaloosa last week. Oklahoma still needs to close with wins over Missouri and LSU to clinch its CFP at-large berth. Missouri RB Ahmad Hardy, who leads the country with 1,346 rushing yards (15 TDs), is coming off a career-best game with 300 yards and 3 TDs last week vs. Mississippi State. The Sooners are 5.5-point favorites. Prediction: Oklahoma 27, Missouri 21

No. 13 Miami (8-2, 4-2 ACC) at Virginia Tech (3-7, 2-4), 12 p.m. on ESPN: The Hurricanes appear to be on the outside looking in on a CFP at-large berth, and were the focus of a lot of misplaced anger from media and fans that they are ranked four spots behind 8-2 Notre Dame despite having a head-to-head win over the Fighting Irish. Well, that win was by three points in Week 1. The Hurricanes have since lost to two presently unranked teams in the last five weeks while Notre Dame has won eight straight games by double-figures. The ranking is fair, and Miami needs a lot of help to find a path into the playoffs. It will surely be looking for style points Saturday as a 17.5-point favorite. Prediction: Miami 44, Virginia Tech 21

Charlotte (1-9) at No. 4 Georgia (9-1), 12:45 p.m. on SEC Network: Georgia also gets a pseudo off week before its finale next Saturday vs. No. 16 Georgia Tech. The Bulldogs are 43.5-point favorites. Prediction: Georgia 51, Charlotte 3

Eastern Illinois (3-8) at No. 10 Alabama (8-2), 2 p.m. on SEC Network+: Ditto for Alabama, which usually schedules a light week ahead of the Iron Bowl vs. Auburn. The Crimson Tide is a 49-point favorite coming off that loss to Oklahoma and will surely want to make sure this one is convincing. Prediction: Alabama 60, Eastern Illinois 9

No. 15 USC (8-2, 6-1 Big Ten) at No. 7 Oregon (9-1, 6-1), 3:30 p.m. on CBS: The game of the week in college football. This likely serves as a CFP elimination game for the loser, though with some help and favorable dominoes around college football Oregon would still be in the conversation at two losses. But it’s possible the Big Ten only gets three teams in, and if the Trojans pull the upset they’d be in the driver’s seat to be that third team after Ohio State and Indiana. The Ducks are 10.5-point favorites. Prediction: Oregon 35, USC 31

Syracuse (3-7) at No. 9 Notre Dame (8-2), 3:30 p.m. on NBC Peacock: The Fighting Irish should be in full control of their playoff path, but with all the scrutiny of their ranking relative to Miami’s, style points wouldn’t hurt. Notre Dame is a 36.5-point favorite. Prediction: Notre Dame 41, Syracuse 13

Kentucky (5-5, 2-5 SEC) at No. 8 Vanderbilt (8-2, 4-2), 3:30 p.m. on ESPN: Vandy is also on the outside looking in at the projected playoff field right now, but there will surely be attrition ahead of the Commodores in the CFP rankings the next few weeks. They just need to take care of business and stay in the conversation. After looking like the worst team in the SEC most of the season, Kentucky has won two straight conference games at Auburn and vs. Florida (plus a third straight over Tennessee Tech). Vandy is an 8.5-point favorite. Prediction: Vanderbilt 36, Kentucky 27

Arkansas (2-8, 0-6 SEC) at No. 17 Texas (7-3, 4-2), 3:30 p.m. on ABC: Texas does get No. 3 undefeated Texas A&M at home next week, and if it wins that game it will really put the CFP committee in a quagmire. First, the Longhorns need to take care of business against an Arkansas team that can put up points if nothing else. Texas already needed overtime to beat Kentucky and Mississippi State this season, so nothing is a given here. The Longhorns are 8.5-point favorites. Prediction: Texas 31, Arkansas 27

No. 24 Tulane (8-2, 5-1 AAC) at Temple (5-5, 3-3), 3:45 p.m. on ESPNU: The Green Wave is in full control of its CFP hopes as the highest-ranked Group of Five conference champion gets an automatic berth onto the 12-team bracket. Tulane is the only G5 team ranked by the CFP committee, but it still has a likely showdown with 9-1 North Texas in the AAC championships game. Tulane did take a head-scratching loss, 48-26 at UTSA, a few weeks ago, so nothing can be assumed here. But with a CFP berth in sight, expect the Green Wave to take care of business as an 8.5-point favorite. Prediction: Tulane 35, Temple 24

Kansas State (5-5, 4-3 Big 12) at No. 12 Utah (8-2, 5-2), 4 p.m. on ESPN2: The Utes are going to need some help and good luck to get into the playoffs, as they don’t control their path to the Big 12 championship game. All Utah can do is keep winning and winning big like it has with all its wins coming by 24 or more points. Kansas State has won three of four after a rough first half of the season. The Utes are 17.5-point favorites. Prediction: Utah 49, Kansas State 28

No. 18 Michigan (8-2, 6-1 Big Ten) at Maryland (4-6, 1-6), 4 p.m. on Big Ten Network: The Wolverines will have their shot to shake up the CFP picture next week when they host No. 1 Ohio State, looking for a fifth straight win over their rivals. But that’s only if they don’t have a let-down game Saturday on the road against reeling Maryland, which has lost six straight. Michigan is a 14.5-point favorite. Prediction: Michigan 27, Maryland 20

TCU (6-4, 3-4 Big 12) at No. 23 Houston (8-2, 5-2), 4 p.m. on FOX: Houston doesn’t have a path to the CFP or really the Big 12 championship game, barring total chaos. But the Cougars can cap a nice season as the most surprising team in the conference with a strong finish. Houston is a 1.5-point favorite. Prediction: TCU 28, Houston 23

Pittsburgh (7-3, 5-1 ACC) at No. 16 Georgia Tech (9-1, 6-1), 7 p.m. on ESPN: The wheels look like they’re coming off for Georgia Tech, which lost at NC State and then nearly lost again to the ACC’s worst team, Boston College, before ultimately winning 36-34 last week. The Yellow Jackets need to either win the ACC championship or beat Pitt and then No. 4 Georgia and hope for an at-large berth into the CFP. Pitt had won five straight before losing big to Notre Dame last week. The Panthers are also still in the ACC championship hunt. Georgia Tech is a 2.5-point favorite. Prediction: Pittsburgh 47, Georgia Tech 45

No. 20 Tennessee (7-3, 3-3 SEC) at Florida (3-7, 2-5), 7:30 p.m. on ABC: This is a rivalry series prone to wild outcomes, so even with an interim coach and a struggling quarterback, The Swamp should be rocking and nothing should be assumed here. Tennessee is a 3.5-point favorite. Prediction: Tennessee 27, Florida 21

No. 21 Illinois (7-3, 4-3 Big Ten) at Wisconsin (3-7, 1-6), 7:30 p.m. on Big Ten Network: Given that Illinois was a top-10 team at one point this season, this isn’t how the Fighting Illini hoped to end up, but it can still be a solid season for the program. Wisconsin upset Washington at home earlier this month, but that’s been the only highlight all fall for the Badgers. Illinois is a 9.5-point favorite. Prediction: Illinois 28, Wisconsin 14

No. 11 BYU (9-1, 6-1 Big 12) at Cincinnati (7-3, 5-2), 8 p.m. on FOX: The Cougars control their path to the Big 12 championship game and a likely rematch with Texas Tech, which won the first meeting earlier this month 29-7. BYU has to win out to make the playoffs, while Cincinnati saw its playoff hopes dissipate with back-to-back losses to Utah and Arizona. BYU is a 2.5-point favorite. Prediction: BYU 33, Cincinnati 24

No. 25 Arizona State (7-3, 5-2 Big 12) at Colorado (3-7, 1-6), 8 p.m. on ESPN2: The Sun Devils need a lot of help to have a chance to back into the Big 12 championship game, but expect them to play like their season is still on the line nonetheless. Colorado has lost five of its last six games. The Sun Devils are 6.5-point favorites. Prediction: Arizona State 37, Colorado 14

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